Human 26S Proteasome Non-ATPase Regulatory Subunit 8 (PSMD8) Peptide (OVA)

Proteasome 26S Subunit, Non ATPase 8 Peptide (OVA) is a Human protein conjugated to OVA. The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a non-ATPase subunit of the 19S regulator. A pseudogene has been identified on chromosome 1.

Target	26S Proteasome Non-ATPase Regulatory Subunit 8 (PSMD8)
Origin	Human
Expression	Synthetic
Tested Applications	WB, SDS-PAGE
Conjugation	OVA
Form	Lyophilized
Purity	> 90%
Reconstitution	To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in PBS, pH 7.4. If a higher concentration is required, the product can be reconstituted directly in PBS, pH 7.4, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex.
Storage	Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P48556 (UniProt, ExPASy)
UniProt Secondary AC	B4DX18, Q6P1L7
UniProt Entry Name	PSMD8_HUMAN
Gene Symbol	PSMD8
GeneID	5714
KEGG	hsa:5714
String	9606.ENSP00000215071
Sequence Fragment	Leu310-Asp327
Buffer	Prior to lyophilization: PBS, pH 7.4.
Activity	Not tested
Concentration	Prior to lyophilization: 200 µg/ml
Availability	Shipped within 5-7 working days.
Note	This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use.

Research Articles on 26S Proteasome Non-ATPase Regulatory Subunit 8 (PSMD8)

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