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Proteasome Subunit Alpha Type 7 (PSMA7) Antibody
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Catalogue No: abx002977
Price:
US$203.00
(Size: 20 µl)
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PSMA7 Antibody is a Rabbit Polyclonal antibody against PSMA7. The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. This gene encodes a member of the peptidase T1A family that functions as a 20S core alpha subunit. The encoded protein interacts with the hepatitis B virus X protein and plays a role in regulating hepatitis C virus internal ribosome entry site (IRES) activity, an activity essential for viral replication. The encoded protein also plays a role in the cellular stress response by regulating hypoxia-inducible factor-1alpha. A pseudogene of this gene is located on the long arm of chromosome 9.
Research Articles on Proteasome Subunit Alpha Type 7 (PSMA7)
| Target | Proteasome Subunit Alpha Type 7 (PSMA7) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | WB, IHC, IF/ICC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/500 - 1/2000, IHC-P: 1/50 - 1/100, IF/ICC: 1/50 - 1/100. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 1-248 of human PSMA7. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | O14818 (UniProt, ExPASy) |
| UniProt Secondary AC | B2R515, Q5JXJ2, Q9BR53, Q9H4K5, Q9UEU8 |
| UniProt Entry Name | PSA7_HUMAN |
| Gene Symbol | PSMA7 |
| GeneID | 5688 |
| NCBI Accession | NP_002783.1 |
| KEGG | hsa:5688 |
| String | 9606.ENSP00000359910 |
| Molecular Weight | Calculated MW: 28 kDa Observed MW: 30 kDa |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Concentration | > 0.2 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |