Prostaglandin E Receptor 2 (PTGER2) Antibody

PTGER2 Antibody is a Rabbit Polyclonal antibody against PTGER2. This gene encodes a receptor for prostaglandin E2, a metabolite of arachidonic acid which has different biologic activities in a wide range of tissues. Mutations in this gene are associated with aspirin-induced susceptibility to asthma. Prostaglandin E2 receptor (53kDa), also known as EP2, is a prostaglandin receptor for prostaglandin E2. It is encoded by the human gene PTGER2. Receptor for prostaglandin E2 (PGE2). The activity of this receptor is mediated by G(s) proteins that stimulate adenylate cyclase. The subsequent raise in intracellular cAMP is responsible for the relaxing effect of this receptor on smooth muscle.

Target	Prostaglandin E Receptor 2 (PTGER2)
Clonality	Polyclonal
Reactivity	Human, Mouse, Rat
Tested Applications	WB, IHC, IF/ICC
Host	Rabbit
Recommended dilutions	WB: 1/500 - 1/2000, IHC-P: 1/50 - 1/200, IF/ICC: 1/100 - 1/200. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	A synthetic peptide corresponding to a sequence within amino acids 1-100 of human PGE receptor EP2 (PTGER2).
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P43116 (UniProt, ExPASy)
UniProt Secondary AC	D3DSC0, Q52LG8
UniProt Entry Name	PE2R2_HUMAN
Gene Symbol	PTGER2
GeneID	5732
NCBI Accession	NP_000947.2
KEGG	hsa:5732
String	9606.ENSP00000245457
Molecular Weight	Calculated MW: 40 kDa Observed MW: 40 kDa
Buffer	PBS, pH 7.3, containing 0.01% thimerosal, 50% glycerol.
Concentration	> 0.2 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Prostaglandin E Receptor 2 (PTGER2)

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