Pumilio Homolog 1 (PUM1) Antibody

PUM1 is a member of the PUF family, evolutionarily conserved RNA-binding proteins related to the Pumilio proteins of Drosophila and the fem-3 mRNA binding factor proteins of C. elegans. This protein contains a sequence-specific RNA binding domain comprised of eight repeats and N and C-terminal flanking regions, and serves as a translational regulator of specific mRNAs by binding to their 3' untranslated regions. The evolutionarily conserved function of this protein in invertebrates and lower vertebrates suggests that the human protein may be involved in translational regulation of embryogenesis, and cell development and differentiation.

Target	Pumilio Homolog 1 (PUM1)
Clonality	Polyclonal
Reactivity	Human
Tested Applications	ELISA, WB, IHC
Host	Rabbit
Recommended dilutions	WB: 1/1000, IHC-P: 1/10 - 1/50. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	KLH-conjugated synthetic peptide between 62-91 amino acids from human PUM1.
Isotype	IgG
Form	Liquid
Purification	Purified through a protein A column, followed by peptide affinity purification.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	Q14671 (UniProt, ExPASy)
UniProt Secondary AC	A8K6W4, B4DG92, D3DPN3, E9PCJ0, Q53HH5, Q5VXY7, Q9HAN1
UniProt Entry Name	PUM1_HUMAN
KEGG	hsa:9698
String	9606.ENSP00000391723
Molecular Weight	Calculated MW: 126 kDa
Buffer	PBS containing 0.09% sodium azide.
Specificity	Predicted to react with Mouse, Chicken and Xenopus PUM1.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Pumilio Homolog 1 (PUM1)

Write a review

Your Name

Your Email Address

PMID

DOI

Your Review

Rating

Continue