Histone-Binding Protein RBBP7 (RBBP7) Antibody

RBBP7 is a ubiquitously expressed nuclear protein and belongs to a highly conserved subfamily of WD-repeat proteins. It is found among several proteins that binds directly to retinoblastoma protein, which regulates cell proliferation. This protein is found in many histone deacetylase complexes, including mSin3 co-repressor complex. It is also present in protein complexes involved in chromatin assembly. This protein can interact with BRCA1 tumor-suppressor gene and may have a role in the regulation of cell proliferation and differentiation.

Target	Histone-Binding Protein RBBP7 (RBBP7)
Clonality	Polyclonal
Reactivity	Human
Tested Applications	ELISA, WB, FCM
Host	Rabbit
Recommended dilutions	WB: 1/1000, FCM: 1/10 - 1/50. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	KLH-conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human RBBP7.
Isotype	IgG
Form	Liquid
Purification	Purified through a protein A column, followed by peptide affinity purification.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	Q16576 (UniProt, ExPASy)
UniProt Secondary AC	Q5JP00
UniProt Entry Name	RBBP7_HUMAN
KEGG	hsa:5931
String	9606.ENSP00000369424
Molecular Weight	Calculated MW: 47.8 kDa
Buffer	PBS containing 0.09% sodium azide.
Specificity	Predicted to react with Mouse, Rat, Cow, Monkey and Xenopus RBBP7.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Histone-Binding Protein RBBP7 (RBBP7)

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