RIMS-Binding Protein 3A (RIMBP3) Antibody

RIM-binding proteins (RIMBPs) serve as adaptors during vesicle fusion and release by forming links between synaptic-vesicle fusion apparatuses and calcium channels. RIMBP3 has been identified as a novel manchette-associated protein, and three members of RIMBP3 are known to exist: RIMBP3A, RIMBP3B and RIMBP3C. Each form of RIMBP3 exists as a large multidomain protein encoding three SH3-domains and two to three fibronectin III repeats. RIMBP3 plays a role in spermatid development and is required for normal sperm morphology and male fertility. RIMBP3 is found at high levels outside of the nervous system, with especially high expression in testis. RIMBP3C (RIMS binding protein 3C), also known as RIMBP3.3, or RIM-BP3.3, is a 1545 amino acid protein.

Target	RIMS-Binding Protein 3A (RIMBP3)
Clonality	Polyclonal
Reactivity	Human
Tested Applications	ELISA, WB
Host	Rabbit
Recommended dilutions	WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	KLH-conjugated synthetic peptide between 180-209 amino acids from the N-terminal region of human RIMBP3.
Isotype	IgG
Form	Liquid
Purification	Purified through a protein A column, followed by peptide affinity purification.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	Q9UFD9 (UniProt, ExPASy)
UniProt Secondary AC	Q8IYP7, Q9BY94, Q9UFQ5
UniProt Entry Name	RIM3A_HUMAN
Gene Symbol	RIMBP3
String	9606.ENSP00000483386
Molecular Weight	Calculated MW: 181 kDa
Buffer	PBS containing 0.09% sodium azide.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on RIMS-Binding Protein 3A (RIMBP3)

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