SUMO1/Sentrin Specific Peptidase 5 (SENP5) Antibody

The reversible posttranslational modification of proteins by the addition of small ubiquitin-like SUMO proteins (see SUMO1; MIM 601912) is required for numerous biologic processes. SUMO-specific proteases, such as SENP5, are responsible for the initial processing of SUMO precursors to generate a C-terminal diglycine motif required for the conjugation reaction. They also have isopeptidase activity for the removal of SUMO from high molecular mass SUMO conjugates (Di Bacco et al., 2006 [PubMed 16738315]).

Target	SUMO1/Sentrin Specific Peptidase 5 (SENP5)
Clonality	Polyclonal
Reactivity	Human
Tested Applications	ELISA, WB
Host	Rabbit
Recommended dilutions	WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	KLH-conjugated synthetic peptide between 718-747 amino acids from the C-terminal region of human SENP5.
Isotype	IgG
Form	Liquid
Purification	Purified through a protein A column, followed by peptide affinity purification.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	Q96HI0 (UniProt, ExPASy)
UniProt Secondary AC	B4DY82, Q96SA5
UniProt Entry Name	SENP5_HUMAN
KEGG	hsa:205564
String	9606.ENSP00000327197
Molecular Weight	Calculated MW: 86.7 kDa
Buffer	PBS containing 0.09% sodium azide.
Specificity	Predicted to react with Mouse and Monkey SENP5.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on SUMO1/Sentrin Specific Peptidase 5 (SENP5)

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