Epsilon-Sarcoglycan (SGCE) Antibody

SGCE Antibody is a Rabbit Polyclonal antibody against SGCE. This gene encodes the epsilon member of the sarcoglycan family. Sarcoglycans are transmembrane proteins that are components of the dystrophin-glycoprotein complex, which link the actin cytoskeleton to the extracellular matrix. Unlike other family members which are predominantly expressed in striated muscle, the epsilon sarcoglycan is more broadly expressed. Mutations in this gene are associated with myoclonus-dystonia syndrome. This gene is imprinted, with preferential expression from the paternal allele. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Target	Epsilon-Sarcoglycan (SGCE)
Clonality	Polyclonal
Reactivity	Human, Mouse
Tested Applications	WB
Host	Rabbit
Recommended dilutions	WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 1-317 of human SGCE.
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	O43556 (UniProt, ExPASy)
UniProt Entry Name	SGCE_HUMAN
Gene Symbol	SGCE
GeneID	8910
OMIM	159900
NCBI Accession	NP_003910.1
HGNC	10808
KEGG	hsa:8910
Ensembl	ENSG00000127990
String	9606.ENSP00000398930
Molecular Weight	Calculated MW: 50 kDa Observed MW: 55 kDa
Buffer	PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol.
Concentration	> 0.2 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Epsilon-Sarcoglycan (SGCE)

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