Sirtuin 3 (SIRT3) Antibody

SIRT3 Antibody is a Rabbit Polyclonal antibody against SIRT3. This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class I of the sirtuin family. Two alternatively spliced transcript variants that encode different proteins have been described for this gene.

Target	Sirtuin 3 (SIRT3)
Clonality	Polyclonal
Reactivity	Human, Mouse, Rat
Tested Applications	WB, IHC, IF/ICC, IP
Host	Rabbit
Recommended dilutions	WB: 1/500 - 1/1000, IHC-P: 1/50 - 1/200, IP: 0.5-4 µg/200-400 µg whole cell extracts, IF/ICC: 1/50 - 1/200. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	A synthetic peptide corresponding to a sequence within amino acids 388-399 of human SIRT3.
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	Q9NTG7 (UniProt, ExPASy)
UniProt Secondary AC	B7Z5U6, Q9Y6E8
UniProt Entry Name	SIR3_HUMAN
Gene Symbol	SIRT3
GeneID	23410
NCBI Accession	NP_036371.1
String	9606.ENSP00000372191
Molecular Weight	Calculated MW: 44 kDa Observed MW: 28/44 kDa
Buffer	PBS, pH 7.3, containing 0.01% thimerosal, 50% glycerol.
Concentration	> 0.2 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Sirtuin 3 (SIRT3)

Write a review

Your Name

Your Email Address

PMID

DOI

Your Review

Rating

Continue