Signaling Lymphocytic Activation Molecule Family Member 1 / CD150 (SLAMF1) Antibody

SLAMF1 Antibody is a Rabbit Polyclonal antibody against SLAMF1. Following occupancy of the T cell receptor by antigen, T cell proliferation and lymphokine production are determined by a second costimulatory signal delivered by a ligand expressed on antigen-presenting cells. SLAM (for signaling lymphocyte-activation molecule, also designated CDw150) is a novel receptor on T cells that, when engaged, potentiates T cell expansion in a CD28-independent manner. SAP (for SLAM-associated protein) contains an SH2 domain and functions to inhibit SH-PTP2 recruitment to the SLAM docking site, an activity induced by Fyn phosphorylation of SLAM. Mutations of the SAP gene may be associated with X-linked lympho-proliferative disease (XLP).

Target	Signaling Lymphocytic Activation Molecule Family Member 1 / CD150 (SLAMF1)
Clonality	Polyclonal
Reactivity	Human, Mouse
Tested Applications	WB
Host	Rabbit
Recommended dilutions	WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 21-237 of human CD150/SLAM.
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	Q13291 (UniProt, ExPASy)
UniProt Secondary AC	Q5W172, Q9HBE8, W0HKK7
UniProt Entry Name	SLAF1_HUMAN
Gene Symbol	SLAMF1
GeneID	6504
NCBI Accession	NP_003028.1
KEGG	hsa:6504
String	9606.ENSP00000306190
Molecular Weight	Calculated MW: 37 kDa Observed MW: 37/65 kDa
Buffer	PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol.
Concentration	> 0.2 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Signaling Lymphocytic Activation Molecule Family Member 1 / CD150 (SLAMF1)

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