Steroidogenic Acute Regulatory Protein, Mitochondrial (STAR) Antibody

The protein encoded by this gene plays a key role in the acute regulation of steroid hormone synthesis by enhancing the conversion of cholesterol into pregnenolone. This protein permits the cleavage of cholesterol into pregnenolone by mediating the transport of cholesterol from the outer mitochondrial membrane to the inner mitochondrial membrane. Mutations in this gene are a cause of congenital lipoid adrenal hyperplasia (CLAH), also called lipoid CAH. A pseudogene of this gene is located on chromosome 13.

Target	Steroidogenic Acute Regulatory Protein, Mitochondrial (STAR)
Clonality	Polyclonal
Reactivity	Human
Tested Applications	ELISA, WB
Host	Rabbit
Recommended dilutions	WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	KLH-conjugated synthetic peptide between 88-117 amino acids from the Central region of human STAR.
Isotype	IgG
Form	Liquid
Purification	Purified through a protein A column, followed by peptide affinity purification.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P49675 (UniProt, ExPASy)
UniProt Secondary AC	Q16396
UniProt Entry Name	STAR_HUMAN
KEGG	hsa:6770
String	9606.ENSP00000276449
Molecular Weight	Calculated MW: 31.9 kDa
Buffer	PBS containing 0.09% sodium azide.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Steroidogenic Acute Regulatory Protein, Mitochondrial (STAR)

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