Ubiquitin/ISG15-Conjugating Enzyme E2 L6 (UBE2L6) Antibody

The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes (E1s), ubiquitin-conjugating enzymes (E2s) and ubiquitin-protein ligases (E3s). UBE2L6 is a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is demonstrated to function in the E6/E6-ap-induced ubiquitination of p53.

Target	Ubiquitin/ISG15-Conjugating Enzyme E2 L6 (UBE2L6)
Clonality	Polyclonal
Reactivity	Human
Tested Applications	ELISA, WB, IHC
Host	Rabbit
Recommended dilutions	WB: 1/1000, IHC-P: 1/10 - 1/50. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	KLH-conjugated synthetic peptide between 123-153 amino acids from the C-terminal region of human UBE2L6.
Isotype	IgG
Form	Liquid
Purification	Purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	O14933 (UniProt, ExPASy)
UniProt Secondary AC	A6NDM6, A8MY53, Q8N5D8, Q9UEZ0
Gene Symbol	UBE2L6
NCBI Accession	NP_004214.1 NP_937826.1
Molecular Weight	Calculated MW: 17.8 kDa
Buffer	PBS containing 0.09% sodium azide.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Ubiquitin/ISG15-Conjugating Enzyme E2 L6 (UBE2L6)

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