Protein Wnt-5a (Wnt5a) Antibody

Wnt5a Antibody is a Rabbit Polyclonal antibody against Wnt5a. The Wnt family includes several secreted glycoproteins that play important roles in animal developmentThere are 19 Wnt genes in the human genome that encode functionally distinct Wnt proteinsWnt members bind to the Frizzled family of seven-pass transmembrane proteins and activate several signaling pathwaysThe canonical Wnt/β-catenin pathway also requires a coreceptor from the low-density lipoprotein receptor familyAberrant activation of Wnt signaling pathways is involved in several types of cancersWnt-5a has been shown to signal through the canonical Wnt pathways as well as through non-canonical pathways and is up-regulated in various types of human cancersIn melanoma, Wnt5a is thought to directly affect cell motility and metastasis.

Target	Protein Wnt-5a (Wnt5a)
Clonality	Polyclonal
Reactivity	Human, Mouse, Rat
Tested Applications	ELISA, WB, IHC
Host	Rabbit
Recommended dilutions	WB: 1/500 - 1/2000, IHC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P41221 (UniProt, ExPASy)
UniProt Secondary AC	A8K4A4, Q6P278
UniProt Entry Name	WNT5A_HUMAN
Gene Symbol	WNT5A
GeneID	7474
KEGG	hsa:7474
String	9606.ENSP00000264634
Buffer	PBS, pH 7.3, containing 0.02% sodium azide and 50% glycerol.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Protein Wnt-5a (Wnt5a)

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