YWHAZ (pS58) Antibody

YWHAZ (pS58) Antibody is a Rabbit Polyclonal antibody against YWHAZ (pS58). This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 99% identical to the mouse, rat and sheep orthologs. The encoded protein interacts with IRS1 protein, suggesting a role in regulating insulin sensitivity. Several transcript variants that differ in the 5' UTR but that encode the same protein have been identified for this gene.

Target	YWHAZ (pS58)
Clonality	Polyclonal
Reactivity	Human, Mouse, Rat
Tested Applications	WB, IF/ICC
Host	Rabbit
Recommended dilutions	WB: 1/500 - 1/2000, IF/ICC: 1/100 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	A phospho specific peptide corresponding to residues surrounding S58 of human YWHAZ
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P63104 (UniProt, ExPASy)
UniProt Entry Name	1433Z_HUMAN
Gene Symbol	YWHAZ
GeneID	7534
KEGG	hsa:7534
String	9606.ENSP00000379287
Molecular Weight	Calculated MW: 28 kDa Observed MW: 28 kDa
Buffer	PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol.
Concentration	> 0.2 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on YWHAZ (pS58)

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